TOP CATEGORY: Chemicals & Materials | Life Sciences | Banking & Finance | ICT Media

Global Darunavir Market Research Report 2024(Status and Outlook)

Global Darunavir Market Research Report 2024(Status and Outlook)

  • Category:Life Sciences
  • Published on : 02 October 2024
  • Pages :107
  • Formats:
  • Report Code:SMR-8009614
OfferClick for best price

Best Price: $2600

Darunavir Market Size, Share 2024


Market size in 2024 US$ 1.89 billion
Forecast Market size by 2030 US$ 2.34 billion
Growth Rate CAGR of 3.6% Number of Pages 107 Pages
The global Darunavir market size was valued at US$ 1.89 billion in 2024 and is projected to reach US$ 2.34 billion by 2030, at a CAGR of 3.6% during the forecast period 2024-2030.

United States Darunavir market size was valued at US$ 615 million in 2024 and is projected to reach US$ 734 million by 2030, at a CAGR of 3.0% during the forecast period 2024-2030.

fallback
Protease inhibitor used in combination therapy for HIV treatment.

Steady growth driven by its efficacy against drug-resistant HIV strains. Increasing adoption in first-line HIV treatment regimens. Development of fixed-dose combinations improving patient adherence.

Report Overview
Darunavir (DRV), sold under the brand name Prezista among others, is an antiretroviral medication used to treat and prevent HIV/AIDS. It is generally recommended for use with other antiretrovirals.
This report provides a deep insight into the global Darunavir market covering all its essential aspects. This ranges from a macro overview of the market to micro details of the market size, competitive landscape, development trend, niche market, key market drivers and challenges, SWOT analysis, value chain analysis, etc.
The analysis helps the reader to shape the competition within the industries and strategies for the competitive environment to enhance the potential profit. Furthermore, it provides a simple framework for evaluating and accessing the position of the business organization. The report structure also focuses on the competitive landscape of the Global Darunavir Market, this report introduces in detail the market share, market performance, product situation, operation situation, etc. of the main players, which helps the readers in the industry to identify the main competitors and deeply understand the competition pattern of the market.
In a word, this report is a must-read for industry players, investors, researchers, consultants, business strategists, and all those who have any kind of stake or are planning to foray into the Darunavir market in any manner.
Global Darunavir Market: Market Segmentation Analysis
The research report includes specific segments by region (country), manufacturers, Type, and Application. Market segmentation creates subsets of a market based on product type, end-user or application, Geographic, and other factors. By understanding the market segments, the decision-maker can leverage this targeting in the product, sales, and marketing strategies. Market segments can power your product development cycles by informing how you create product offerings for different segments.
Key Company
  • Janssen Therapeutics
  • Mylan
  • Teva
  • Cipla
  • Lupin
  • Hetero

Market Segmentation (by Type)
  • Tablet
  • Oral suspension

Market Segmentation (by Application)
  • Hospital
  • Drug store

Geographic Segmentation
  • North America (USA, Canada, Mexico)
  • Europe (Germany, UK, France, Russia, Italy, Rest of Europe)
  • Asia-Pacific (China, Japan, South Korea, India, Southeast Asia, Rest of Asia-Pacific)
  • South America (Brazil, Argentina, Columbia, Rest of South America)
  • The Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria, South Africa, Rest of MEA)

Key Benefits of This Market Research:
  • Industry drivers, restraints, and opportunities covered in the study
  • Neutral perspective on the market performance
  • Recent industry trends and developments
  • Competitive landscape & strategies of key players
  • Potential & niche segments and regions exhibiting promising growth covered
  • Historical, current, and projected market size, in terms of value
  • In-depth analysis of the Darunavir Market
  • Overview of the regional outlook of the Darunavir Market:

Key Reasons to Buy this Report:
Access to date statistics compiled by our researchers. These provide you with historical and forecast data, which is analyzed to tell you why your market is set to change
This enables you to anticipate market changes to remain ahead of your competitors
You will be able to copy data from the Excel spreadsheet straight into your marketing plans, business presentations, or other strategic documents
The concise analysis, clear graph, and table format will enable you to pinpoint the information you require quickly
Provision of market value (USD Billion) data for each segment and sub-segment
Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market
Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region
Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled
Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players
The current as well as the future market outlook of the industry concerning recent developments which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions
Includes in-depth analysis of the market from various perspectives through Porter
Report Attributes Report Details
Report Title Global Darunavir Market Research Report 2024(Status and Outlook)
Market size in 2024 US$ 1.89 billion
Forecast Market size by 2030 US$ 2.34 billion
Growth Rate CAGR of 3.6%
Historical Year 2018 to 2022 (Data from 2010 can be provided as per availability)
Base Year 2023
Forecast Year 2031
Number of Pages 107 Pages
Customization Available Yes, the report can be customized as per your need.

TABLE OF CONTENTS

Table of Contents
1 Research Methodology and Statistical Scope
1.1 Market Definition and Statistical Scope of Darunavir
1.2 Key Market Segments
1.2.1 Darunavir Segment by Type
1.2.2 Darunavir Segment by Application
1.3 Methodology & Sources of Information
1.3.1 Research Methodology
1.3.2 Research Process
1.3.3 Market Breakdown and Data Triangulation
1.3.4 Base Year
1.3.5 Report Assumptions & Caveats
2 Darunavir Market Overview
2.1 Global Market Overview
2.1.1 Global Darunavir Market Size (M USD) Estimates and Forecasts (2019-2030)
2.1.2 Global Darunavir Sales Estimates and Forecasts (2019-2030)
2.2 Market Segment Executive Summary
2.3 Global Market Size by Region
3 Darunavir Market Competitive Landscape
3.1 Global Darunavir Sales by Manufacturers (2019-2024)
3.2 Global Darunavir Revenue Market Share by Manufacturers (2019-2024)
3.3 Darunavir Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
3.4 Global Darunavir Average Price by Manufacturers (2019-2024)
3.5 Manufacturers Darunavir Sales Sites, Area Served, Product Type
3.6 Darunavir Market Competitive Situation and Trends
3.6.1 Darunavir Market Concentration Rate
3.6.2 Global 5 and 10 Largest Darunavir Players Market Share by Revenue
3.6.3 Mergers & Acquisitions, Expansion
4 Darunavir Industry Chain Analysis
4.1 Darunavir Industry Chain Analysis
4.2 Market Overview of Key Raw Materials
4.3 Midstream Market Analysis
4.4 Downstream Customer Analysis
5 The Development and Dynamics of Darunavir Market
5.1 Key Development Trends
5.2 Driving Factors
5.3 Market Challenges
5.4 Market Restraints
5.5 Industry News
5.5.1 New Product Developments
5.5.2 Mergers & Acquisitions
5.5.3 Expansions
5.5.4 Collaboration/Supply Contracts
5.6 Industry Policies
6 Darunavir Market Segmentation by Type
6.1 Evaluation Matrix of Segment Market Development Potential (Type)
6.2 Global Darunavir Sales Market Share by Type (2019-2024)
6.3 Global Darunavir Market Size Market Share by Type (2019-2024)
6.4 Global Darunavir Price by Type (2019-2024)
7 Darunavir Market Segmentation by Application
7.1 Evaluation Matrix of Segment Market Development Potential (Application)
7.2 Global Darunavir Market Sales by Application (2019-2024)
7.3 Global Darunavir Market Size (M USD) by Application (2019-2024)
7.4 Global Darunavir Sales Growth Rate by Application (2019-2024)
8 Darunavir Market Segmentation by Region
8.1 Global Darunavir Sales by Region
8.1.1 Global Darunavir Sales by Region
8.1.2 Global Darunavir Sales Market Share by Region
8.2 North America
8.2.1 North America Darunavir Sales by Country
8.2.2 U.S.
8.2.3 Canada
8.2.4 Mexico
8.3 Europe
8.3.1 Europe Darunavir Sales by Country
8.3.2 Germany
8.3.3 France
8.3.4 U.K.
8.3.5 Italy
8.3.6 Russia
8.4 Asia Pacific
8.4.1 Asia Pacific Darunavir Sales by Region
8.4.2 China
8.4.3 Japan
8.4.4 South Korea
8.4.5 India
8.4.6 Southeast Asia
8.5 South America
8.5.1 South America Darunavir Sales by Country
8.5.2 Brazil
8.5.3 Argentina
8.5.4 Columbia
8.6 Middle East and Africa
8.6.1 Middle East and Africa Darunavir Sales by Region
8.6.2 Saudi Arabia
8.6.3 UAE
8.6.4 Egypt
8.6.5 Nigeria
8.6.6 South Africa
9 Key Companies Profile
9.1 Janssen Therapeutics
9.1.1 Janssen Therapeutics Darunavir Basic Information
9.1.2 Janssen Therapeutics Darunavir Product Overview
9.1.3 Janssen Therapeutics Darunavir Product Market Performance
9.1.4 Janssen Therapeutics Business Overview
9.1.5 Janssen Therapeutics Darunavir SWOT Analysis
9.1.6 Janssen Therapeutics Recent Developments
9.2 Mylan
9.2.1 Mylan Darunavir Basic Information
9.2.2 Mylan Darunavir Product Overview
9.2.3 Mylan Darunavir Product Market Performance
9.2.4 Mylan Business Overview
9.2.5 Mylan Darunavir SWOT Analysis
9.2.6 Mylan Recent Developments
9.3 Teva
9.3.1 Teva Darunavir Basic Information
9.3.2 Teva Darunavir Product Overview
9.3.3 Teva Darunavir Product Market Performance
9.3.4 Teva Darunavir SWOT Analysis
9.3.5 Teva Business Overview
9.3.6 Teva Recent Developments
9.4 Cipla
9.4.1 Cipla Darunavir Basic Information
9.4.2 Cipla Darunavir Product Overview
9.4.3 Cipla Darunavir Product Market Performance
9.4.4 Cipla Business Overview
9.4.5 Cipla Recent Developments
9.5 Lupin
9.5.1 Lupin Darunavir Basic Information
9.5.2 Lupin Darunavir Product Overview
9.5.3 Lupin Darunavir Product Market Performance
9.5.4 Lupin Business Overview
9.5.5 Lupin Recent Developments
9.6 Hetero
9.6.1 Hetero Darunavir Basic Information
9.6.2 Hetero Darunavir Product Overview
9.6.3 Hetero Darunavir Product Market Performance
9.6.4 Hetero Business Overview
9.6.5 Hetero Recent Developments
10 Darunavir Market Forecast by Region
10.1 Global Darunavir Market Size Forecast
10.2 Global Darunavir Market Forecast by Region
10.2.1 North America Market Size Forecast by Country
10.2.2 Europe Darunavir Market Size Forecast by Country
10.2.3 Asia Pacific Darunavir Market Size Forecast by Region
10.2.4 South America Darunavir Market Size Forecast by Country
10.2.5 Middle East and Africa Forecasted Consumption of Darunavir by Country
11 Forecast Market by Type and by Application (2025-2030)
11.1 Global Darunavir Market Forecast by Type (2025-2030)
11.1.1 Global Forecasted Sales of Darunavir by Type (2025-2030)
11.1.2 Global Darunavir Market Size Forecast by Type (2025-2030)
11.1.3 Global Forecasted Price of Darunavir by Type (2025-2030)
11.2 Global Darunavir Market Forecast by Application (2025-2030)
11.2.1 Global Darunavir Sales (Kilotons) Forecast by Application
11.2.2 Global Darunavir Market Size (M USD) Forecast by Application (2025-2030)
12 Conclusion and Key Findings

LIST OF TABLES & FIGURES

List of Tables
Table 1. Introduction of the Type
Table 2. Introduction of the Application
Table 3. Market Size (M USD) Segment Executive Summary
Table 4. Darunavir Market Size Comparison by Region (M USD)
Table 5. Global Darunavir Sales (Kilotons) by Manufacturers (2019-2024)
Table 6. Global Darunavir Sales Market Share by Manufacturers (2019-2024)
Table 7. Global Darunavir Revenue (M USD) by Manufacturers (2019-2024)
Table 8. Global Darunavir Revenue Share by Manufacturers (2019-2024)
Table 9. Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Darunavir as of 2022)
Table 10. Global Market Darunavir Average Price (USD/Ton) of Key Manufacturers (2019-2024)
Table 11. Manufacturers Darunavir Sales Sites and Area Served
Table 12. Manufacturers Darunavir Product Type
Table 13. Global Darunavir Manufacturers Market Concentration Ratio (CR5 and HHI)
Table 14. Mergers & Acquisitions, Expansion Plans
Table 15. Industry Chain Map of Darunavir
Table 16. Market Overview of Key Raw Materials
Table 17. Midstream Market Analysis
Table 18. Downstream Customer Analysis
Table 19. Key Development Trends
Table 20. Driving Factors
Table 21. Darunavir Market Challenges
Table 22. Global Darunavir Sales by Type (Kilotons)
Table 23. Global Darunavir Market Size by Type (M USD)
Table 24. Global Darunavir Sales (Kilotons) by Type (2019-2024)
Table 25. Global Darunavir Sales Market Share by Type (2019-2024)
Table 26. Global Darunavir Market Size (M USD) by Type (2019-2024)
Table 27. Global Darunavir Market Size Share by Type (2019-2024)
Table 28. Global Darunavir Price (USD/Ton) by Type (2019-2024)
Table 29. Global Darunavir Sales (Kilotons) by Application
Table 30. Global Darunavir Market Size by Application
Table 31. Global Darunavir Sales by Application (2019-2024) & (Kilotons)
Table 32. Global Darunavir Sales Market Share by Application (2019-2024)
Table 33. Global Darunavir Sales by Application (2019-2024) & (M USD)
Table 34. Global Darunavir Market Share by Application (2019-2024)
Table 35. Global Darunavir Sales Growth Rate by Application (2019-2024)
Table 36. Global Darunavir Sales by Region (2019-2024) & (Kilotons)
Table 37. Global Darunavir Sales Market Share by Region (2019-2024)
Table 38. North America Darunavir Sales by Country (2019-2024) & (Kilotons)
Table 39. Europe Darunavir Sales by Country (2019-2024) & (Kilotons)
Table 40. Asia Pacific Darunavir Sales by Region (2019-2024) & (Kilotons)
Table 41. South America Darunavir Sales by Country (2019-2024) & (Kilotons)
Table 42. Middle East and Africa Darunavir Sales by Region (2019-2024) & (Kilotons)
Table 43. Janssen Therapeutics Darunavir Basic Information
Table 44. Janssen Therapeutics Darunavir Product Overview
Table 45. Janssen Therapeutics Darunavir Sales (Kilotons), Revenue (M USD), Price (USD/Ton) and Gross Margin (2019-2024)
Table 46. Janssen Therapeutics Business Overview
Table 47. Janssen Therapeutics Darunavir SWOT Analysis
Table 48. Janssen Therapeutics Recent Developments
Table 49. Mylan Darunavir Basic Information
Table 50. Mylan Darunavir Product Overview
Table 51. Mylan Darunavir Sales (Kilotons), Revenue (M USD), Price (USD/Ton) and Gross Margin (2019-2024)
Table 52. Mylan Business Overview
Table 53. Mylan Darunavir SWOT Analysis
Table 54. Mylan Recent Developments
Table 55. Teva Darunavir Basic Information
Table 56. Teva Darunavir Product Overview
Table 57. Teva Darunavir Sales (Kilotons), Revenue (M USD), Price (USD/Ton) and Gross Margin (2019-2024)
Table 58. Teva Darunavir SWOT Analysis
Table 59. Teva Business Overview
Table 60. Teva Recent Developments
Table 61. Cipla Darunavir Basic Information
Table 62. Cipla Darunavir Product Overview
Table 63. Cipla Darunavir Sales (Kilotons), Revenue (M USD), Price (USD/Ton) and Gross Margin (2019-2024)
Table 64. Cipla Business Overview
Table 65. Cipla Recent Developments
Table 66. Lupin Darunavir Basic Information
Table 67. Lupin Darunavir Product Overview
Table 68. Lupin Darunavir Sales (Kilotons), Revenue (M USD), Price (USD/Ton) and Gross Margin (2019-2024)
Table 69. Lupin Business Overview
Table 70. Lupin Recent Developments
Table 71. Hetero Darunavir Basic Information
Table 72. Hetero Darunavir Product Overview
Table 73. Hetero Darunavir Sales (Kilotons), Revenue (M USD), Price (USD/Ton) and Gross Margin (2019-2024)
Table 74. Hetero Business Overview
Table 75. Hetero Recent Developments
Table 76. Global Darunavir Sales Forecast by Region (2025-2030) & (Kilotons)
Table 77. Global Darunavir Market Size Forecast by Region (2025-2030) & (M USD)
Table 78. North America Darunavir Sales Forecast by Country (2025-2030) & (Kilotons)
Table 79. North America Darunavir Market Size Forecast by Country (2025-2030) & (M USD)
Table 80. Europe Darunavir Sales Forecast by Country (2025-2030) & (Kilotons)
Table 81. Europe Darunavir Market Size Forecast by Country (2025-2030) & (M USD)
Table 82. Asia Pacific Darunavir Sales Forecast by Region (2025-2030) & (Kilotons)
Table 83. Asia Pacific Darunavir Market Size Forecast by Region (2025-2030) & (M USD)
Table 84. South America Darunavir Sales Forecast by Country (2025-2030) & (Kilotons)
Table 85. South America Darunavir Market Size Forecast by Country (2025-2030) & (M USD)
Table 86. Middle East and Africa Darunavir Consumption Forecast by Country (2025-2030) & (Units)
Table 87. Middle East and Africa Darunavir Market Size Forecast by Country (2025-2030) & (M USD)
Table 88. Global Darunavir Sales Forecast by Type (2025-2030) & (Kilotons)
Table 89. Global Darunavir Market Size Forecast by Type (2025-2030) & (M USD)
Table 90. Global Darunavir Price Forecast by Type (2025-2030) & (USD/Ton)
Table 91. Global Darunavir Sales (Kilotons) Forecast by Application (2025-2030)
Table 92. Global Darunavir Market Size Forecast by Application (2025-2030) & (M USD)
List of Figures
Figure 1. Product Picture of Darunavir
Figure 2. Data Triangulation
Figure 3. Key Caveats
Figure 4. Global Darunavir Market Size (M USD), 2019-2030
Figure 5. Global Darunavir Market Size (M USD) (2019-2030)
Figure 6. Global Darunavir Sales (Kilotons) & (2019-2030)
Figure 7. Evaluation Matrix of Segment Market Development Potential (Type)
Figure 8. Evaluation Matrix of Segment Market Development Potential (Application)
Figure 9. Evaluation Matrix of Regional Market Development Potential
Figure 10. Darunavir Market Size by Country (M USD)
Figure 11. Darunavir Sales Share by Manufacturers in 2023
Figure 12. Global Darunavir Revenue Share by Manufacturers in 2023
Figure 13. Darunavir Market Share by Company Type (Tier 1, Tier 2 and Tier 3): 2023
Figure 14. Global Market Darunavir Average Price (USD/Ton) of Key Manufacturers in 2023
Figure 15. The Global 5 and 10 Largest Players: Market Share by Darunavir Revenue in 2023
Figure 16. Evaluation Matrix of Segment Market Development Potential (Type)
Figure 17. Global Darunavir Market Share by Type
Figure 18. Sales Market Share of Darunavir by Type (2019-2024)
Figure 19. Sales Market Share of Darunavir by Type in 2023
Figure 20. Market Size Share of Darunavir by Type (2019-2024)
Figure 21. Market Size Market Share of Darunavir by Type in 2023
Figure 22. Evaluation Matrix of Segment Market Development Potential (Application)
Figure 23. Global Darunavir Market Share by Application
Figure 24. Global Darunavir Sales Market Share by Application (2019-2024)
Figure 25. Global Darunavir Sales Market Share by Application in 2023
Figure 26. Global Darunavir Market Share by Application (2019-2024)
Figure 27. Global Darunavir Market Share by Application in 2023
Figure 28. Global Darunavir Sales Growth Rate by Application (2019-2024)
Figure 29. Global Darunavir Sales Market Share by Region (2019-2024)
Figure 30. North America Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 31. North America Darunavir Sales Market Share by Country in 2023
Figure 32. U.S. Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 33. Canada Darunavir Sales (Kilotons) and Growth Rate (2019-2024)
Figure 34. Mexico Darunavir Sales (Units) and Growth Rate (2019-2024)
Figure 35. Europe Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 36. Europe Darunavir Sales Market Share by Country in 2023
Figure 37. Germany Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 38. France Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 39. U.K. Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 40. Italy Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 41. Russia Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 42. Asia Pacific Darunavir Sales and Growth Rate (Kilotons)
Figure 43. Asia Pacific Darunavir Sales Market Share by Region in 2023
Figure 44. China Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 45. Japan Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 46. South Korea Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 47. India Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 48. Southeast Asia Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 49. South America Darunavir Sales and Growth Rate (Kilotons)
Figure 50. South America Darunavir Sales Market Share by Country in 2023
Figure 51. Brazil Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 52. Argentina Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 53. Columbia Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 54. Middle East and Africa Darunavir Sales and Growth Rate (Kilotons)
Figure 55. Middle East and Africa Darunavir Sales Market Share by Region in 2023
Figure 56. Saudi Arabia Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 57. UAE Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 58. Egypt Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 59. Nigeria Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 60. South Africa Darunavir Sales and Growth Rate (2019-2024) & (Kilotons)
Figure 61. Global Darunavir Sales Forecast by Volume (2019-2030) & (Kilotons)
Figure 62. Global Darunavir Market Size Forecast by Value (2019-2030) & (M USD)
Figure 63. Global Darunavir Sales Market Share Forecast by Type (2025-2030)
Figure 64. Global Darunavir Market Share Forecast by Type (2025-2030)
Figure 65. Global Darunavir Sales Forecast by Application (2025-2030)
Figure 66. Global Darunavir Market Share Forecast by Application (2025-2030)

REPORT PURCHASE OPTIONS

USD Single User Price
USD Multi User Price
USD Enterprise Price

---- OR ----

Frequently Asked Questions ?

  • Upto 24 hrs - Working days
  • Upto 48 hrs max - Weekends and public holidays
  • Single User License
    A license granted to one user. Rules or conditions might be applied for e.g. the use of electric files (PDFs) or printings, depending on product.

  • Multi user License
    A license granted to multiple users.

  • Site License
    A license granted to a single business site/establishment.

  • Corporate License, Global License
    A license granted to all employees within organisation access to the product.
  • Online Payments with PayPal and CCavenue
  • Wire Transfer/Bank Transfer
  • Email
  • Hard Copy

Our Key Features

  • Data Accuracy and Reliability
  • Data Security
  • Customized Research
  • Trustworthy
  • Competitive Offerings
check discount